Researchers at Cleveland Clinic have discovered new mechanisms that show that eating red meat on a regular basis can increase the risk of heart disease, in addition to the role of intestinal bacteria in that process.
The medical researcher Dr. Stanley Hazen, Ph.D. indicates that the TMAO (trimethylamine N-oxide), a by-product of intestinal bacteria formed during digestion, can lead to the development of cardiovascular diseases, including heart attacks.
TMAO occurs when intestinal bacteria digest choline, lecithin, and carnitine, nutrients that are abundant in animal products such as red meat, liver, and other animal products.
According to the Institute of Forensic Pathology, in the Dominican Republic, 37% of the deaths recorded are caused by cardiovascular diseases.
“We know that lifestyle factors are critical for cardiovascular health, and these findings are based on our previous research on the link of TMAO with heart disease, provide additional evidence of how dietary interventions can be an effective treatment strategy to reduce TMAO levels and decrease the subsequent risk of heart disease, “says Dr. Stanley Hazen.
The study conducted by Cleveland Clinic included 113 participants who sequentially (in random order) received full meal plans prepared with protein sources of red meat, white meat or non-meat (mostly vegetarian), in 25 percent of their daily calories.
All the participants had a washing diet among the meal plans.
After a month of a red meat diet, the vast majority of study participants experienced an elevation in blood and urine TMAO levels.
On average, levels of TMAO in the blood increased approximately three times during the red meat diet, compared to the white meat diet, with some patients showing an increase of more than 10 times.
Similar increases were observed in the urine.
However, after the patients discontinued the red meat diet, the levels of TMAO in the blood and urine decreased during the following month.
Having a balanced diet and reducing red meat, could improve your lifestyle, and prevent the levels of TMAO increase, which may cause chronic heart disease.
The European Heart Journal research was supported by grants from the National Institutes of Health (NIH), the Office of Dietary Supplements, and the Clinical and Translational Science Unit of the University of California, San Francisco.
The study of the Journal of Clinical Investigation was supported by NIH and from the Office of Dietary Supplements and the Leducq Foundation grants.
About Cleveland Clinic
Cleveland Clinic is a nonprofit academic center with several specialties that integrates clinic and hospital care with research and education.
Located in Cleveland, Ohio, it was founded in 1921 by four physicians with the vision of providing patient care based on the principles of cooperation and innovation.
Cleveland Clinic has been a pioneer in many medical advances, including coronary artery bypass surgery and the first face transplant in the United States.